• How stable are quantitative sensory testing measurements over time? Report on 10-week reliability and agreement of results in healthy volunteers. 

      Nothnagel, Helen; Puta, Christian; Lehmann, Thomas; Baumbach, Phillip; Menard, Martha B; Gabriel, Brunhild; Gabriel, Holger HW; Weiss, Thomas; Musial, Frauke (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-29)
      Background: Quantitative sensory testing (QST) is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were ...
    • Recruitment and inclusion procedures as "pain killers" in clinical trials? 

      Nothnagel, Helen; Brown Menard, Martha; Kvarstein, Gunnvald; Norheim, Arne Johan; Weiss, Thomas; Puta, Christian; Mist, Scott D; Musial, Frauke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-03)
      <p><i>Background - </i>Recruitment and inclusion procedures in clinical trials are time critical. This holds particularly true for studies investigating patients with fluctuating symptom patterns, like those with chronic neck pain. In a feasibility study on neck pain, we found a clinically relevant decrease in pain ratings within the recruitment period. This paper analyses the phenomenon and gives ...